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Catalogue Information
Field name	Details
Nuova numerazione	80307
Collocazione	UPS BIBL CENTR SL-II-521
Autore	INSEL, C.
Titolo	Aberrant striatal tracking of reward magnitude in youth with current or past-year depression. Parte componente di periodico
Descrizione fisica	pp. 44-56.
Nota generale	Estratto da: Journal of Abnormal Psychology 2019, 128, 1.
Riassunto	Reward dysfunction is often present in youth with major depressive disorder (MDD), but the specific neurobiological bases underlying reward valuation deficits remain unclear. Behaviorally, HC accelerated button press responses on high stakes compared to low-stakes trials, whereas MDD did not alter response speed across stakes. Neurally, HC increased recruitment of the ventral and dorsal striatum, canonical reward-processing regions, for high-magnitude versus low-magnitude rewards. However, the MDD group did not exhibit striatal magnitude tracking for low versus high rewards-an effect independent of MDD recency, MDD symptom severity, comorbid anxiety and substance use disorders, and psychiatric medication use. In contrast, striatal recruitment for overall reward reactivity, measured by comparing striatal activity for reward and loss feedback, was similar in the MDD and HC groups. However, reward reactivity was negatively correlated with current depression symptom severity in the MDD group. Taken together, these findings suggest that whereas reward reactivity may vary with current depression severity, reward magnitude tracking may represent an important aberrant valuation process in youth with depression-independent of symptom severity and recency. This valuation deficit may have implications for maladaptive motivation and learning observed in youth with MDD.
Tipo di documento	RICERCA.
Soggetto	DISTURBI.
	PSICOPATOLOGIA.
	DEPRESSIONE.
	ADOLESCENTI.
	VALUTAZIONE.
	USA.
Ambito	Psicologico
Autore Secondario	GLENN, C. R.
	NOCK, M. K.
	SOMERVILLE, L. H.
Titolo correlato	Journal of Abnormal Psychology 2019, 128, 1.
Accesso online	Scheda EBSCO

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Aberrant striatal tracking of reward magnitude in youth with current or past-year depression.